Avascular Necrosis Market Demand, Volume, Applications, Growth And Forecasts To 2026
Avascular
necrosis (AVN), also called osteonecrosis, ischemic bone necrosis, or
aseptic necrosis, is a condition that occurs due to loss of blood
flow to the bone. The condition mostly occurs in the hip however,
other common sites include ankle, knee, and shoulder. Individuals
between the age of 20 and 50 years are more susceptible to avascular
necrosis. Most cases of avascular necrosis occur due to an underlying
health problem or injury. Moreover, factors such as increased intake
of corticosteroids and alcohol may cause fatty substances to build in
the blood vessels and decrease the blood supply to the bones,
eventually causing avascular necrosis. Treatment for this condition
depends on a number of factors, including age, disease stage,
location, and amount of bone damage.
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Market
Dynamics
Growth
of avascular necrosis market is primarily driven by factors such as
increasing incidence of avascular necrosis, high demand for
non-invasive treatment, and increasing dependence on surgery to cure
avascular necrosis. According to Bone Therapeutics report in 2017,
around 170,000 patients were suffering from avascular necrosis in the
U.S., Europe, and Japan. Moreover, side effects from various
medicines taken during cancer, HIV/AIDS, osteoporosis,
osteoarthritis, blood disorders, or medical treatment such as
chemotherapy, radiation therapy, high-dosage of steroids, and organ
transplants can increase chances of developing avascular necrosis.
However, delay in diagnosis due to asymptomatic nature of this
condition at early stage and high cost of surgical treatments for
avascular necrosis are the major factors hampering growth of the
avascular necrosis market.
Key
features of the study:
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This report provides in-depth analysis of the avascular necrosis market, market size (US$ Mn), and Compound Annual Growth Rate (CAGR (%)) for the forecast period: 2018 – 2026, considering 2017, as the base year
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It elucidates potential revenue opportunity across different segments and explains attractive investment proposition matrix for this market
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This study also provides key insights about market drivers, restraints, opportunities, new product launches or approval, market trends, regional outlook, and competitive strategies adopted by leading players
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It profiles key players in the global avascular necrosis market based on the following parameters – company overview, financial performance, product portfolio, geographical presence, distribution strategies, key developments, and strategies
Detailed
Segmentation:
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Global Avascular Necrosis Market, By Type:
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Trauma Related Avascular Necrosis
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Non-Trauma Related Avascular Necrosis
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Global Avascular Necrosis Market, By Treatment:
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Drug Based
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Surgery
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Increasing
Alcohol Consumption and Use of Corticosteroids are Expected to Drive
Growth of the Avascular Necrosis Market
Excessive
alcohol consumption and long-term, high dose systemic corticosteroid
use are the major risk factors for avascular necrosis. According to
World Journal of Orthopedics, 2015, avascular necrosis usually
affects people between 30 and 50 years of age. Also, from the same
source, about 10,000 to 20,000 people develop osteonecrosis each year
in the U.S. According to National Organization for Rare Disorders’
2015 data, alcohol consumption and corticosteroid use affects about
30% and 35% of all people with non-traumatic avascular necrosis,
respectively across the globe.
Other
risk factors or conditions associated with non-traumatic
osteonecrosis include autoimmune disease, cancer, decompression
disease (Caisson disease), Gaucher disease, pancreatitis, HIV
infection, and blood disorders such as sickle cell disease. Certain
medical treatments including radiation therapy and chemotherapy can
also cause osteonecrosis. Moreover, people who have undergone organ
transplants are at high developmental risk of osteonecrosis.
Avascular
Necrosis Market - Competitive Landscape
Key
players operating in the global avascular necrosis market include
Bone Therapeutics, Boehringer Ingelheim GmbH, Bayer AG, Enzo Biochem
Inc., Ethicon Inc., Eli Lilly and Company, Grifols SA, Integra
LifeSciences Corporation, K-Stemcell Co Ltd., Medtronic Plc, Merck
KGaA, Pfizer Inc., Sanofi SA, Stryker Corporation, Wright Medical
Group N.V., and Zimmer Biomet Holdings. Manufacturers are focusing on
advancements in treatment technologies such as gene therapy and stem
cell-based treatment for avascular necrosis.
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Necrosis Market
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